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How genetically dissimilar does a couple have to be to no longer risk producing children with genetic disorders due to inbreeding? Is it okay to have children with a 4th cousin? 3rd cousin? 2nd cousin? And similarly, does genetic dissimilarity at some point stop being beneficial for couples?

This study found that 3rd and 4th cousin couples have higher fertility rates than the average, and suggest that this is the sweet spot between inbreeding depression and genetic incompatibility due to a condition called 'Rh incompatibility'. What do you guys think?


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